mwr Xer site-specific recombination is hypersensitive to DNA supercoiling

The multiresistance plasmid pJHCMW1, first identified in a Klebsiella pneumoniae strain isolated from a neonate with meningitis, includes a Xer recombination site, mwr, with unique characteristics. Efficiency of resolution of mwr-containing plasmid dimers is strongly dependent on the osmotic pressur...

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Bibliographic Details
Main Authors: Trigueros, Sonia, Tran, Tung, Sorto, Nohemy, Newmark, Jason, Colloms, Sean D., Sherratt, David J., Tolmasky, Marcelo E.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699498/
https://ncbi.nlm.nih.gov/pubmed/19359357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp208
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