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Innate immune recognition of bacterial ligands by NAIPs dictates inflammasome specificity
Inflammasomes are a family of cytosolic multiprotein complexes that initiate innate immune responses to pathogenic microbes by activating the CASPASE1 (CASP1) protease(1,2). Although genetic data support a critical role for inflammasomes in immune defense and inflammatory diseases(3), the molecular...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3184209/ https://ncbi.nlm.nih.gov/pubmed/21874021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10394 |
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