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Innate immune recognition of bacterial ligands by NAIPs dictates inflammasome specificity

Inflammasomes are a family of cytosolic multiprotein complexes that initiate innate immune responses to pathogenic microbes by activating the CASPASE1 (CASP1) protease(1,2). Although genetic data support a critical role for inflammasomes in immune defense and inflammatory diseases(3), the molecular...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kofoed, Eric M., Vance, Russell E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184209/
https://ncbi.nlm.nih.gov/pubmed/21874021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature10394
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