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NAIP inflammasomes give the NOD to bacterial ligands
NLRs are innate immune sensors that monitor the sanctity of the cytosolic compartment. Tenthorey et al. reveal a novel ligand-sensing interface within regions of the oligomerization domain (NOD/NACHT) of the NAIPs, rather than within the leucine-rich repeats (LRR), as was anticipated.
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| Publicado no: | Trends Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4254492/ https://ncbi.nlm.nih.gov/pubmed/25443492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2014.10.002 |
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