Identification of a Conserved Anti-Apoptotic Protein That Modulates the Mitochondrial Apoptosis Pathway

Here we identified an evolutionarily highly conserved and ubiquitously expressed protein (C9orf82) that shows structural similarities to the death effector domain of apoptosis-related proteins. RNAi knockdown of C9orf82 induced apoptosis in A-549 and MCF7/casp3-10b lung and breast carcinoma cells, r...

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Autors principals: Zhang, Yu, Johansson, Elisabet, Miller, Marian L., Jänicke, Reiner U., Ferguson, Donald J., Plas, David, Meller, Jarek, Anderson, Marshall W.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184134/
https://ncbi.nlm.nih.gov/pubmed/21980415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025284
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