Emergence of the rtA181T/sW172* mutant increased the risk of hepatoma occurrence in patients with lamivudine-resistant chronic hepatitis B

BACKGROUND: Development of the hepatitis B virus (HBV) rtA181T/sW172* mutant could occur during prolonged lamivudine (LAM) therapy, conferring cross resistance to adefovir. Recent studies demonstrated an increased oncogenic potential of this mutant in NIH3T3 cells. In this study, we aimed to investi...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Yeh, Chau-Ting, Chen, Tiffany, Hsu, Chao-Wei, Chen, Yi-Cheng, Lai, Ming-Wei, Liang, Kung-Hao, Chen, Tse-Ching
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184121/
https://ncbi.nlm.nih.gov/pubmed/21933446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-398
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker