Antiviral efficacy of entecavir for hepatitis B virus rtA181V/T mutants

BACKGROUND: The amino acid substitution at position 181 of the Hepatitis B virus (HBV) polymerase is a multi-drug resistance affecting both the L-nucleoside and acyclic phosphonate nucleotide groups. Data is limited on the efficacy of entecavir (ETV) rescuing chronic hepatitis B (CHB) patients with...

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Bibliografiske detaljer
Udgivet i:Virol J
Main Authors: Li, Ping, Geng, Jiabao, Li, Wei, Xu, Xiaobing, Zhang, Xin, Zheng, Wenkai, Yu, Yuecheng, Yang, Zhiguo, Wang, Maorong
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5379510/
https://ncbi.nlm.nih.gov/pubmed/28376852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-017-0739-z
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