HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat

BACKGROUND: Maturation inhibitors are an experimental class of antiretrovirals that inhibit Human Immunodeficiency Virus (HIV) particle maturation, the structural rearrangement required to form infectious virus particles. This rearrangement is triggered by the ordered cleavage of the precursor Gag p...

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Hlavní autoři: Fun, Axel, van Maarseveen, Noortje M, Pokorná, Jana, Maas, Renée EM, Schipper, Pauline J, Konvalinka, Jan, Nijhuis, Monique
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2011
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184055/
https://ncbi.nlm.nih.gov/pubmed/21864346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-70
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