HIV-1 protease inhibitor mutations affect the development of HIV-1 resistance to the maturation inhibitor bevirimat

BACKGROUND: Maturation inhibitors are an experimental class of antiretrovirals that inhibit Human Immunodeficiency Virus (HIV) particle maturation, the structural rearrangement required to form infectious virus particles. This rearrangement is triggered by the ordered cleavage of the precursor Gag p...

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Detalhes bibliográficos
Main Authors: Fun, Axel, van Maarseveen, Noortje M, Pokorná, Jana, Maas, Renée EM, Schipper, Pauline J, Konvalinka, Jan, Nijhuis, Monique
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184055/
https://ncbi.nlm.nih.gov/pubmed/21864346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-70
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