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Stochastic processes strongly influence HIV-1 evolution during suboptimal protease-inhibitor therapy
It has long been assumed that HIV-1 evolution is best described by deterministic evolutionary models because of the large population size. Recently, however, it was suggested that the effective population size (N(e)) may be rather small, thereby allowing chance to influence evolution, a situation be...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC24392/ https://ncbi.nlm.nih.gov/pubmed/9826719 |
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