Protein folding from a highly disordered denatured state: The folding pathway of chymotrypsin inhibitor 2 at atomic resolution

Previous experimental and theoretical studies have produced high-resolution descriptions of the native and folding transition states of chymotrypsin inhibitor 2 (CI2). In similar fashion, here we use a combination of NMR experiments and molecular dynamics simulations to examine the conformations pop...

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Bibliografische gegevens

Gepubliceerd in:	Proc Natl Acad Sci U S A
Hoofdauteurs:	Kazmirski, Steven L., Wong, Kam-Bo, Freund, Stefan M. V., Tan, Yee-Joo, Fersht, Alan R., Daggett, Valerie
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	National Academy of Sciences 2001
Onderwerpen:	Biological Sciences
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31838/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274353/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071054398
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