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Protein folding from a highly disordered denatured state: The folding pathway of chymotrypsin inhibitor 2 at atomic resolution

Previous experimental and theoretical studies have produced high-resolution descriptions of the native and folding transition states of chymotrypsin inhibitor 2 (CI2). In similar fashion, here we use a combination of NMR experiments and molecular dynamics simulations to examine the conformations pop...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Kazmirski, Steven L., Wong, Kam-Bo, Freund, Stefan M. V., Tan, Yee-Joo, Fersht, Alan R., Daggett, Valerie
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC31838/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11274353/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.071054398
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