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Distinct Temporal and Anatomical Distributions of Amyloid-β and Tau Abnormalities following Controlled Cortical Impact in Transgenic Mice

Traumatic brain injury (TBI) is a major environmental risk factor for Alzheimer's disease. Intracellular accumulations of amyloid-β and tau proteins have been observed within hours following severe TBI in humans. Similar abnormalities have been recapitulated in young 3xTg-AD mice subjected to t...

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Detalhes bibliográficos
Main Authors: Tran, Hien T., Sanchez, Laura, Esparza, Thomas J., Brody, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3183029/
https://ncbi.nlm.nih.gov/pubmed/21980472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025475
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