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Spatially distinct atrophy is linked to β-amyloid and tau in preclinical Alzheimer disease
OBJECTIVES: To determine whether an MRI-based Alzheimer disease (AD) signature biomarker can detect tau-related neurodegeneration in preclinical AD, and to assess whether AD signature cortical thinning is associated with cognitive changes in cognitively normal (CN) older individuals. METHODS: In a l...
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| Published in: | Neurology |
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| Main Authors: | , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Lippincott Williams & Wilkins
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366088/ https://ncbi.nlm.nih.gov/pubmed/25716355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000001401 |
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