Cross-sectional and longitudinal atrophy is preferentially associated with tau rather than amyloid β positron emission tomography pathology

INTRODUCTION: Structural magnetic resonance imaging is a marker of gray matter health and decline that is sensitive to impaired cognition and Alzheimer's disease pathology. Prior work has shown that both amyloid β (Aβ) and tau biomarkers are related to cortical thinning, but it is unclear what...

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Vydáno v:Alzheimers Dement (Amst)
Hlavní autoři: Gordon, Brian A., McCullough, Austin, Mishra, Shruti, Blazey, Tyler M., Su, Yi, Christensen, John, Dincer, Aylin, Jackson, Kelley, Hornbeck, Russ C., Morris, John C., Ances, Beau M., Benzinger, Tammie L.S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Special Section: State of the Field: Advances in Neuroimaging from the 2017 Alzheimer’s Imaging Consortium. (Guest Editors: Drs. David Wolk, Victor Villemagne & Bradford Dickerson)
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956934/
https://ncbi.nlm.nih.gov/pubmed/29780869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2018.02.003
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