Tau positron emission tomography imaging in tauopathies: The added hurdle of off-target binding

Ligands targeting tau for use with positron emission tomography have rapidly been developed during the past several years, enabling the in vivo study of tau pathology in patients with Alzheimer's disease and related non-Alzheimer's disease tauopathies. Several candidate compounds have been...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Lemoine, Laetitia, Leuzy, Antoine, Chiotis, Konstantinos, Rodriguez-Vieitez, Elena, Nordberg, Agneta
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Special Section: State of the Field: Advances in Neuroimaging from the 2017 Alzheimer’s Imaging Consortium. (Guest Editors: Drs. David Wolk, Victor Villemagne & Bradford Dickerson)
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5956931/
https://ncbi.nlm.nih.gov/pubmed/29780868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dadm.2018.01.007
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