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Identification and Characterization of a Novel Integrin-Linked Kinase Inhibitor

Integrin-linked kinase (ILK) represents a relevant target for cancer therapy in light of its role in promoting oncogenesis and tumor progression. Through the screening of an in-house focused compound library, we identified N-Methyl-3-(1-(4-(piperazin-1-yl)phenyl)-5-(4′-(trifluoromethyl)-[1,1′-biphen...

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Autors principals: Lee, Su-Lin, Hsu, En-Chi, Chou, Chih-Chien, Chuang, Hsiao-Ching, Bai, Li-Yuan, Kulp, Samuel K., Chen, Ching-Shih
Format: Artigo
Idioma:Inglês
Publicat: 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182772/
https://ncbi.nlm.nih.gov/pubmed/21823616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2007744
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