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Target Validation: Linking Target and Chemical Properties to Desired Product Profile

The discovery of drugs is a lengthy, high-risk and expensive business taking at least 12 years and is estimated to cost upwards of US$800 million for each drug to be successfully approved for clinical use. Much of this cost is driven by the late phase clinical trials and therefore the ability to ter...

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Detalhes bibliográficos
Main Authors: Wyatt, Paul G, Gilbert, Ian H, Read, Kevin D, Fairlamb, Alan H
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers Ltd 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182078/
https://ncbi.nlm.nih.gov/pubmed/21401506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/156802611795429185
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