Targeting granzyme B to tumor cells using a yoked human chorionic gonadotropin

PURPOSE: Luteinizing hormone receptor (LHR) is found in abundance on human ovarian, breast, endometrial and prostate carcinomas but at only low levels on non-gonadal tissues. To selectively kill LHR-expressing tumors, granzyme B (GrB) was linked to a protein in which both chains of human chorionic g...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kanatani, Isao, Lin, Xinjian, Yuan, Xiaoqin, Manorek, Gerald, Shang, Xiying, Cheung, Lawrence H., Rosenblum, Michael G., Howell, Stephen B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Springer-Verlag 2011
Gaiak:
Original Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180622/
https://ncbi.nlm.nih.gov/pubmed/21327682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-011-1573-4
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