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Integrin αV modulates the cellular pharmacology of copper and cisplatin by regulating expression of the influx transporter CTR1

The αV integrin is expressed in most cancer cells where it regulates a diverse array of cellular functions essential to the initiation, progression and metastasis of solid tumors. However, little is known about how αV integrin modulates cellular sensitivity to chemotherapeutic agents, particularly t...

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Publicado en:Oncoscience
Main Authors: Lin, Xinjian, Shang, Xiying, Manorek, Gerald, Fofana, Mariama, Stephen B., Howell
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4278295/
https://ncbi.nlm.nih.gov/pubmed/25594011
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