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Copper transporters and chaperones CTR1, CTR2, ATOX1, and CCS as determinants of cisplatin sensitivity

The development of resistance to cisplatin (cDDP) is commonly accompanied by reduced drug uptake or increased efflux. Previous studies in yeast and murine embryonic fibroblasts have reported that the copper (Cu) transporters and chaperones participate in the uptake, efflux, and intracellular distrib...

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Bibliografiske detaljer
Udgivet i:Metallomics
Main Authors: Bompiani, Kristin M., Tsai, Cheng-Yu, Achatz, Felix P., Liebig, Janika K., Howell, Stephen B.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025354/
https://ncbi.nlm.nih.gov/pubmed/27157188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6mt00076b
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