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Regiospecific inhibition of DNA duplication by antisense phosphate-methylated oligodeoxynucleotides.
A new synthesis route for long phosphate-methylated oligodeoxynucleotides is described, which were used as antisense inhibitors of the DNA replication. Phosphate-methylated oligomers hybridize more strongly with natural DNA than their natural analogues, due to the absence of electrostatic interstran...
Tallennettuna:
| Päätekijät: | , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1989
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC318031/ https://ncbi.nlm.nih.gov/pubmed/2748337 |
| Tagit: |
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