Multi-species Analyses of Direct Activators of the Constitutive Androstane Receptor

The constitutive androstane receptor (CAR; NR1I3) is a member of the nuclear receptor superfamily and functions as an important xenochemical sensor and transcriptional modulator in mammalian cells. Upon chemical activation, CAR undergoes nuclear translocation and heterodimerization with the retinoid...

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Bibliographic Details
Main Authors: Omiecinski, Curtis J., Coslo, Denise M., Chen, Tao, Laurenzana, Elizabeth M., Peffer, Richard C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2011
Subjects:
Molecular Toxicology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179682/
https://ncbi.nlm.nih.gov/pubmed/21778469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr191
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