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In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets
The constitutive androstane receptor (CAR; NR1I3) is a nuclear receptor orchestrating complex roles in cell and systems biology. Species differences in CAR’s effector pathways remain poorly understood, including its role in regulating liver tumor promotion. We developed transgenic mouse models to as...
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| Vydáno v: | Nucleic Acids Res |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6144799/ https://ncbi.nlm.nih.gov/pubmed/30102401 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky692 |
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