In vivo genome-wide binding interactions of mouse and human constitutive androstane receptors reveal novel gene targets

The constitutive androstane receptor (CAR; NR1I3) is a nuclear receptor orchestrating complex roles in cell and systems biology. Species differences in CAR’s effector pathways remain poorly understood, including its role in regulating liver tumor promotion. We developed transgenic mouse models to as...

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Bibliografske podrobnosti
izdano v:Nucleic Acids Res
Main Authors: Niu, Ben, Coslo, Denise M, Bataille, Alain R, Albert, Istvan, Pugh, B Franklin, Omiecinski, Curtis J
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2018
Teme:
Genomics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6144799/
https://ncbi.nlm.nih.gov/pubmed/30102401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky692
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