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Multi-species Analyses of Direct Activators of the Constitutive Androstane Receptor

The constitutive androstane receptor (CAR; NR1I3) is a member of the nuclear receptor superfamily and functions as an important xenochemical sensor and transcriptional modulator in mammalian cells. Upon chemical activation, CAR undergoes nuclear translocation and heterodimerization with the retinoid...

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Detalhes bibliográficos
Main Authors: Omiecinski, Curtis J., Coslo, Denise M., Chen, Tao, Laurenzana, Elizabeth M., Peffer, Richard C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179682/
https://ncbi.nlm.nih.gov/pubmed/21778469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfr191
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