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Robust Antigen Specific Th17 T Cell Response to Group A Streptococcus Is Dependent on IL-6 and Intranasal Route of Infection

Group A streptococcus (GAS, Streptococcus pyogenes) is the cause of a variety of clinical conditions, ranging from pharyngitis to autoimmune disease. Peptide-major histocompatibility complex class II (pMHCII) tetramers have recently emerged as a highly sensitive means to quantify pMHCII-specific CD4...

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Autors principals: Dileepan, Thamotharampillai, Linehan, Jonathan L., Moon, James J., Pepper, Marion, Jenkins, Marc K., Cleary, Patrick P.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178561/
https://ncbi.nlm.nih.gov/pubmed/21966268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002252
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