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Induction of TGF-β1 and TGF-β1–dependent predominant Th17 differentiation by group A streptococcal infection
Recurrent group A Streptococcus (GAS) tonsillitis and associated autoimmune diseases indicate that the immune response to this organism can be ineffective and pathological. TGF-β1 is recognized as an essential signal for generation of regulatory T cells (Tregs) and T helper (Th) 17 cells. Here, the...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2851870/ https://ncbi.nlm.nih.gov/pubmed/20231435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904831107 |
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