Group A Streptococcus intranasal infection promotes CNS infiltration by streptococcal-specific Th17 cells

Group A streptococcal (GAS) infection induces the production of Abs that cross-react with host neuronal proteins, and these anti-GAS mimetic Abs are associated with autoimmune diseases of the CNS. However, the mechanisms that allow these Abs to cross the blood-brain barrier (BBB) and induce neuropat...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Dileepan, Thamotharampillai, Smith, Erica D., Knowland, Daniel, Hsu, Martin, Platt, Maryann, Bittner-Eddy, Peter, Cohen, Brenda, Southern, Peter, Latimer, Elizabeth, Harley, Earl, Agalliu, Dritan, Cleary, P. Patrick
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701547/
https://ncbi.nlm.nih.gov/pubmed/26657857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI80792
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