Phlebotomine salivas inhibit immune inflammation-induced neutrophil migration via an autocrine DC-derived PGE(2)/IL-10 sequential pathway

In the present study, we investigated whether saliva from Phlebotomus papatasi and Phlebotomus duboscqi inhibited antigen-induced neutrophil migration and the mechanisms involved in these effects. The pretreatment of immunized mice with salivary gland extracts (SGE) of both phlebotomines inhibited O...

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Main Authors: Carregaro, Vanessa, Valenzuela, Jesus G., Cunha, Thiago M., Verri, Waldiceu A., Grespan, Renata, Matsumura, Graziela, Ribeiro, José M. C., Elnaiem, Dia-Eldin, Silva, João S., Cunha, Fernando Q.
Format: Artigo
Sprog:Inglês
Udgivet: The Society for Leukocyte Biology 2008
Fag:
Pathogenesis and Host Defense
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3178508/
https://ncbi.nlm.nih.gov/pubmed/18390928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1107797
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