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Nucleosides Present on Phlebotomine Saliva Induce Immunossuppression and Promote the Infection Establishment
BACKGROUND: Sand fly saliva plays a crucial role in establishing Leishmania infection. We identified adenosine (ADO) and adenosine monophosphate (AMP) as active pharmacologic compounds present in Phlebotomus papatasi saliva that inhibit dendritic cell (DC) functions through a PGE(2)/IL 10-dependent...
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| Publicado no: | PLoS Negl Trop Dis |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4388340/ https://ncbi.nlm.nih.gov/pubmed/25849562 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003600 |
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