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Identifying apicoplast-targeting antimalarials using high-throughput compatible approaches
Malarial parasites have evolved resistance to all previously used therapies, and recent evidence suggests emerging resistance to the first-line artemisinins. To identify antimalarials with novel mechanisms of action, we have developed a high-throughput screen targeting the apicoplast organelle of Pl...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Federation of American Societies for Experimental Biology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177575/ https://ncbi.nlm.nih.gov/pubmed/21746861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-187401 |
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