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Identifying apicoplast-targeting antimalarials using high-throughput compatible approaches
Malarial parasites have evolved resistance to all previously used therapies, and recent evidence suggests emerging resistance to the first-line artemisinins. To identify antimalarials with novel mechanisms of action, we have developed a high-throughput screen targeting the apicoplast organelle of Pl...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Federation of American Societies for Experimental Biology
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177575/ https://ncbi.nlm.nih.gov/pubmed/21746861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-187401 |
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