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A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop

The essential splicing factor Prp24 contains four RNA Recognition Motif (RRM) domains, and functions to anneal U6 and U4 RNAs during spliceosome assembly. Here, we report the structure and characterization of the C-terminal RRM4. This domain adopts a novel non-canonical RRM fold with two additional...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Martin-Tumasz, Stephen, Richie, Ashley C., Clos, Lawrence J., Brow, David A., Butcher, Samuel E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177201/
https://ncbi.nlm.nih.gov/pubmed/21653550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr455
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