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A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop

The essential splicing factor Prp24 contains four RNA Recognition Motif (RRM) domains, and functions to anneal U6 and U4 RNAs during spliceosome assembly. Here, we report the structure and characterization of the C-terminal RRM4. This domain adopts a novel non-canonical RRM fold with two additional...

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書誌詳細
主要な著者: Martin-Tumasz, Stephen, Richie, Ashley C., Clos, Lawrence J., Brow, David A., Butcher, Samuel E.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3177201/
https://ncbi.nlm.nih.gov/pubmed/21653550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr455
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