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A novel occluded RNA recognition motif in Prp24 unwinds the U6 RNA internal stem loop
The essential splicing factor Prp24 contains four RNA Recognition Motif (RRM) domains, and functions to anneal U6 and U4 RNAs during spliceosome assembly. Here, we report the structure and characterization of the C-terminal RRM4. This domain adopts a novel non-canonical RRM fold with two additional...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Oxford University Press
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3177201/ https://ncbi.nlm.nih.gov/pubmed/21653550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr455 |
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