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Structure and functional implications of a complex containing a segment of U6 RNA bound by a domain of Prp24

U6 RNA plays a critical role in pre-mRNA splicing. Assembly of U6 into the spliceosome requires a significant structural rearrangement and base-pairing with U4 RNA. In the yeast Saccharomyces cerevisiae, this process requires the essential splicing factor Prp24. We present the characterization and s...

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Bibliografski detalji
Glavni autori: Martin-Tumasz, Stephen, Reiter, Nicholas J., Brow, David A., Butcher, Samuel E.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2844626/
https://ncbi.nlm.nih.gov/pubmed/20181740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1913310
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