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The N- and C-terminal RNA recognition motifs of splicing factor Prp24 have distinct functions in U6 RNA binding

Prp24 is an essential yeast U6 snRNP protein with four RNA recognition motifs (RRMs) that facilitates the association of U4 and U6 snRNPs during spliceosome assembly. Genetic interactions led to the proposal that RRMs 2 and 3 of Prp24 bind U6 RNA, while RRMs 1 and 4 bind U4 RNA. However, the functio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: KWAN, SHARON S., BROW, DAVID A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Copyright 2005 by RNA Society 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370765/
https://ncbi.nlm.nih.gov/pubmed/15811912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2010905
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