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Homocysteine-Mediated Modulation of Mitochondrial Dynamics in Retinal Ganglion Cells

PURPOSE. To evaluate the effect of excess homocysteine on the regulation of retinal ganglion cell mitochondrial dynamics. METHODS. Mice deficient in cystathionine-β-synthase (cbs) were used as a model of hyperhomocysteinemia. Gene and protein expression analyses of Opa1 and Fis1 were performed on cb...

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Detalhes bibliográficos
Main Authors: Ganapathy, Preethi S., Perry, Richard L., Tawfik, Amany, Smith, Robert M., Perry, Elizabeth, Roon, Penny, Bozard, B. Renee, Ha, Yonju, Smith, Sylvia B.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176036/
https://ncbi.nlm.nih.gov/pubmed/21642619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7256
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