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Homocysteine-Mediated Modulation of Mitochondrial Dynamics in Retinal Ganglion Cells

PURPOSE. To evaluate the effect of excess homocysteine on the regulation of retinal ganglion cell mitochondrial dynamics. METHODS. Mice deficient in cystathionine-β-synthase (cbs) were used as a model of hyperhomocysteinemia. Gene and protein expression analyses of Opa1 and Fis1 were performed on cb...

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Bibliographische Detailangaben
Hauptverfasser: Ganapathy, Preethi S., Perry, Richard L., Tawfik, Amany, Smith, Robert M., Perry, Elizabeth, Roon, Penny, Bozard, B. Renee, Ha, Yonju, Smith, Sylvia B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Association for Research in Vision and Ophthalmology, Inc. 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176036/
https://ncbi.nlm.nih.gov/pubmed/21642619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.11-7256
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