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The Role of N-Methyl-D-Aspartate Receptor Activation in Homocysteine-Induced Death of Retinal Ganglion Cells

PURPOSE. Elevated plasma homocysteine has been implicated in glaucoma, a vision disorder characterized by retinal ganglion cell death. The toxic potential of homocysteine to ganglion cells is known, but the mechanisms are not clear. A mechanism of homocysteine-induced death of cerebral neurons is vi...

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Detalhes bibliográficos
Main Authors: Ganapathy, Preethi S., White, Richard E., Ha, Yonju, Bozard, B. Renee, McNeil, Paul L., Caldwell, R. William, Kumar, Sanjiv, Black, Stephen M., Smith, Sylvia B.
Formato: Artigo
Idioma:Inglês
Publicado em: Association for Research in Vision and Ophthalmology, Inc. 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176067/
https://ncbi.nlm.nih.gov/pubmed/21436276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-6870
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