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LRIG1 negatively regulates the oncogenic EGF receptor mutant EGFRvIII
Epidermal growth factor receptor (EGFR) mutation is frequently observed in human cancer and contributes to the growth, survival and therapeutic resistance of tumors. EGFRvIII is an oncogenic EGFR mutant resulting from the deletion of exons 2–7 and is the most common EGFR mutant observed in glioblast...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3175812/ https://ncbi.nlm.nih.gov/pubmed/18542056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.185 |
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