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ERK-mediated negative feedback regulation of oncogenic EGFRvIII in glioblastoma cells
Epidermal growth factor receptor variant III (EGFRvIII) is the most common active EGFR mutant in glioblastoma multiforme (GBM). The expression of this mutant often correlates with a poor patient prognosis due to its ability to extend downstream signaling. The EGFR pathway is controlled by a negative...
Enregistré dans:
| Publié dans: | Oncol Lett |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
D.A. Spandidos
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7399944/ https://ncbi.nlm.nih.gov/pubmed/32782566 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2020.11760 |
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