Conditional Deletion of Histone Deacetylase 1 in T Cells Leads to Enhanced Airway Inflammation and Increased Th2 Cytokine Production

Chromatin modifications, such as reversible histone acetylation, play a key role in the regulation of T cell development and function. However, the role of individual histone deacetylases (HDACs) in T cells is less well understood. In this article, we show by conditional gene targeting that T cell-s...

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Main Authors: Grausenburger, Reinhard, Bilic, Ivan, Boucheron, Nicole, Zupkovitz, Gordin, El-Housseiny, Lamia, Tschismarov, Roland, Zhang, Yu, Rembold, Martina, Gaisberger, Martin, Hartl, Arnulf, Epstein, Michelle M., Matthias, Patrick, Seiser, Christian, Ellmeier, Wilfried
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
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Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175530/
https://ncbi.nlm.nih.gov/pubmed/20702731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903610
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