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Hedgehog Signaling: Networking to Nurture a Pro-Malignant Tumor Microenvironment

In addition to its role in development, the Hedgehog (Hh) pathway has been shown to be an active participant in cancer development, progression, and metastasis. While the pathway is activated by autocrine signaling by Hh ligands, it can also initiate paracrine signaling with cells in the microenviro...

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Main Authors: Harris, Lillianne G., Samant, Rajeev S., Shevde, Lalita A.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175256/
https://ncbi.nlm.nih.gov/pubmed/21775419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0175
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