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Hedgehog Signaling in Tumor Cells Facilitates Osteoblast-Enhanced Osteolytic Metastases

The remodeling process in bone yields numerous cytokines and chemokines that mediate crosstalk between osteoblasts and osteoclasts and also serve to attract and support metastatic tumor cells. The metastatic tumor cells disturb the equilibrium in bone that manifests as skeletal complications. The He...

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Detalhes bibliográficos
Main Authors: Das, Shamik, Tucker, J. Allan, Khullar, Shikha, Samant, Rajeev S., Shevde, Lalita A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3315536/
https://ncbi.nlm.nih.gov/pubmed/22479615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034374
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