The effect of the histone deacetylase inhibitor M344 on BRCA1 expression in breast and ovarian cancer cells

BACKGROUND: The inhibition of Breast Cancer 1 (BRCA1) expression sensitizes breast and ovarian cancer cells to platinum chemotherapy. However, therapeutically relevant agents that target BRCA1 expression have not been identified. Our recent report suggested the potential of the histone deacetylase (...

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Main Authors: Weberpals, Johanne I, O'Brien, Anna M, Niknejad, Nima, Garbuio, Kyla D, Clark-Knowles, Katherine V, Dimitroulakos, Jim
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
主題:
Primary Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175148/
https://ncbi.nlm.nih.gov/pubmed/21854619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-11-29
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