TRANSGENE-MEDIATED EXPRESSION OF TUMOR NECROSIS FACTOR SOLUBLE RECEPTOR ATTENUATES MORPHINE TOLERANCE IN RATS

Opiate/narcotic analgesics are the most effective treatments for chronic severe pain, but their clinical utility is often hampered by the development of analgesic tolerance. Recent evidence suggests chronic morphine may activate glial cells to release proinflammatory cytokines. In this study, we use...

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Bibliografiske detaljer
Main Authors: Sun, Jingxia, Liu, Shue, Mata, Marina, Fink, David J., Hao, Shuanglin
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3175012/
https://ncbi.nlm.nih.gov/pubmed/21614028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2011.76
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