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Transgene-mediated enkephalin expression attenuates signs of naloxone-precipitated morphine withdrawal in rats with neuropathic pain

Chronic morphine exposure induces physical dependence and tolerance. Previous studies have shown that there is a decrease in met-enkephalin levels in states of morphine physical dependence, and that increasing enkephalin during opiate physical withdrawal ameliorates the severity of the morphine with...

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Detaylı Bibliyografya
Asıl Yazarlar: Hao, Shuanglin, Hu, Jian, Fink, David J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607474/
https://ncbi.nlm.nih.gov/pubmed/18761380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2008.08.005
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