The Role of TNFα in the Periaqueductal Gray During Naloxone-Precipitated Morphine Withdrawal in Rats

Tolerance and dependence are common complications of long-term treatment of pain with opioids, which substantially limit the long-term use of these drugs. The mechanisms underlying these phenomena are poorly understood. Studies have implicated the midbrain periaqueductal gray (PAG) in the pathogenes...

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Bibliografiske detaljer
Main Authors: Hao, Shuanglin, Liu, Shue, Zheng, Xuexing, Zheng, Wenwen, Ouyang, Handong, Mata, Marina, Fink, David J
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3055683/
https://ncbi.nlm.nih.gov/pubmed/21068718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2010.197
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