טוען...
Increased folding and channel activity of a rare cystic fibrosis mutant with CFTR modulators
Cystic fibrosis (CF) is a lethal recessive genetic disease caused by mutations in the CFTR gene. The gene product is a PKA-regulated anion channel that is important for fluid and electrolyte transport in the epithelia of lung, gut, and ducts of the pancreas and sweat glands. The most common CFTR mut...
שמור ב:
| Main Authors: | , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Physiological Society
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174745/ https://ncbi.nlm.nih.gov/pubmed/21642448 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00044.2011 |
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