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Analysis of CFTR Folding and Degradation in Transiently Transfected Cells
Misfolding and premature degradation of F508del-CFTR is the major cause of cystic fibrosis. Components of the ubiquitin-proteasome system function on the surface of the endoplasmic reticulum to select misfolded proteins for degradation. The folding status of F508del-CFTR is monitored by at least two...
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| Pubblicato in: | Methods Mol Biol |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4460993/ https://ncbi.nlm.nih.gov/pubmed/21594788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-117-8_15 |
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