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Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase

Persistent pulmonary hypertension of the newborn (PPHN) is associated with decreased blood vessel density that contributes to increased pulmonary vascular resistance. Previous studies showed that uncoupled endothelial nitric oxide (NO) synthase (eNOS) activity and increased NADPH oxidase activity re...

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Bibliografiske detaljer
Main Authors: Teng, Ru-Jeng, Du, Jianhai, Xu, Hao, Bakhutashvili, Ivane, Eis, Annie, Shi, Yang, Pritchard, Kirkwood A., Konduri, Girija G.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174740/
https://ncbi.nlm.nih.gov/pubmed/21622842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00316.2010
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