Sepiapterin improves angiogenesis of pulmonary artery endothelial cells with in utero pulmonary hypertension by recoupling endothelial nitric oxide synthase

Persistent pulmonary hypertension of the newborn (PPHN) is associated with decreased blood vessel density that contributes to increased pulmonary vascular resistance. Previous studies showed that uncoupled endothelial nitric oxide (NO) synthase (eNOS) activity and increased NADPH oxidase activity re...

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Main Authors: Teng, Ru-Jeng, Du, Jianhai, Xu, Hao, Bakhutashvili, Ivane, Eis, Annie, Shi, Yang, Pritchard, Kirkwood A., Konduri, Girija G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174740/
https://ncbi.nlm.nih.gov/pubmed/21622842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00316.2010
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