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Increased superoxide production contributes to the impaired angiogenesis of fetal pulmonary arteries with in utero pulmonary hypertension

Persistent pulmonary hypertension of newborn (PPHN) is associated with impaired pulmonary vasodilation at birth. Previous studies demonstrated that a decrease in angiogenesis contributes to this failure of postnatal adaptation. We investigated the hypothesis that oxidative stress from NADPH oxidase...

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Detalhes bibliográficos
Principais autores: Teng, Ru-Jeng, Eis, Annie, Bakhutashvili, Ivane, Arul, Nandini, Konduri, Girija G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2711810/
https://ncbi.nlm.nih.gov/pubmed/19429773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.90455.2008
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